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DAR No 3: Brivaracetam. Briviact® for epylepsia (partial-onset seizures)
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Brivaracetam: one more antiepileptic drug
- Brivaracetam is an antiepileptic drug used as an add-on treatment, with a similar structure to that of levetiracetam.
- No direct comparisons have been performed with brivaracetam and other antiepileptic drugs. A response rate near 40% has been obtained with brivaracetam 100-200 mg/day in pivotal placebo-controlled trials.
- Its safety profile is similar to that of levetiracetam, although the experience is limited. Its most common adverse events include dizziness, somnolence, and fatigue.
- Brivaracetam does not make any contribution to therapy as add-on treatment in patients with partial-onset seizures who are unresponsive to other antiepileptic drugs.
