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DTB No 4. Lixisenatide, Lyxumia® in type 2 Diabetes Mellitus

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One more, but not getting ahead


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  • There are no clinical trials on the impact on mortality and the micro and macrovascular complications of diabetes.
  • It has only shown greater efficacy in the reduction of HbA1C (difference vs placebo between -0.32% and -0.74%).
  • Long-term safety remains unknown (thyroid gland related, cardiovascular adverse effects and pancreatitis)
  • There are no advantages in efficacy, safety, posology or cost vs either the antidiabetic agents currently available or other GLP-1 agonists.
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