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DAR No 3. Grass pollen extract (Oralair®) for allergic rhinitis
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An expensive, long-term preventive treatment of modest efficacy
- An allergen extract of five grass pollens is indicated for the management of allergic rhinitis caused by grass pollen with clinically relevant symptoms and diagnosed with specific tests.
- The allergenic extract has shown modest efficacy in trials compared to placebo.
- There are no comparative trials with other immunotherapies.
- A high percentage of patients included in the trials suffered local adverse reactions, especially children, of which the most frequent was oral pruritus (32%). Although rare, there is a risk of severe adverse reactions (angioedema, dysphagia, and respiratory problems).
