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DAR No 6: Fentanyl pectin nasal (PecFent®) spray in breaktrough pain
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Nasal route of administration with no advantages regarding efficacy or safety
- Fentanyl pectin nasal spray represents a different route of administration for opiods, although there is no improvement with regard to the safety profile.
- In comparison to oral morphine, pain relief after 15 minutes was favourable for fentanyl pectin nasal spray, while there were no differences between both treatments after 10 minutes.
- There is a risk of confusion regarding dose modifications with other formulations of fentanyl especially with Instanyl in cases of 100 μg doses: NEVER make a dosefor- dose switch (microgram for microgram).
- It can be an alternative in patients with oral intolerance.
