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DAR No 2: Amlodipin + Atorvastatin
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A combination that makes no sense
- The combination of amlodipin-atorvastatin is indicated in the prevention of cardiovascular events in hypertensive patients with three other concomitant risk factors, and with normal or mildly elevated cholesterol levels.
- The efficacy of statins to reduce cardiovascular risk in primary prevention in patients with normal cholesterol levels has not been sufficiently demonstrated.
- The addition of atorvastatin in patients under treatment with amlodipin in the indication mentioned increases the risk of adverse reactions and the cost of treatment with no clear health benefits. Therefore this combination is not justified.
